Search | Virtual Health Library

1.

The IRG1-itaconate axis protects from cholesterol-induced inflammation and atherosclerosis.

Cyr, Yannick; Bozal, Fazli K; Barcia Durán, José Gabriel; Newman, Alexandra A C; Amadori, Letizia; Smyrnis, Panagiotis; Gourvest, Morgane; Das, Dayasagar; Gildea, Michael; Kaur, Ravneet; Zhang, Tracy; Wang, Kristin M; Von Itter, Richard; Schlegel, P Martin; Dupuis, Samantha D; Sanchez, Bernard F; Schmidt, Ann Marie; Fisher, Edward A; van Solingen, Coen; Giannarelli, Chiara; Moore, Kathryn J.

Proc Natl Acad Sci U S A ; 121(15): e2400675121, 2024 Apr 09.

Article in English | MEDLINE | ID: mdl-38564634

2.

Obesity research: Moving from bench to bedside to population.

Schmidt, Ann Marie.

PLoS Biol ; 21(12): e3002448, 2023 Dec.

Article in English | MEDLINE | ID: mdl-38048365

3.

Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity.

Theophall, Gregory G; Ramirez, Lisa M S; Premo, Aaron; Reverdatto, Sergey; Manigrasso, Michaele B; Yepuri, Gautham; Burz, David S; Ramasamy, Ravichandran; Schmidt, Ann Marie; Shekhtman, Alexander.

J Biol Chem ; 299(11): 105342, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37832872

4.

Experimentally Induced Peripheral Venous Congestion Exacerbates Inflammation, Oxidative Stress, and Neurohormonal and Endothelial Cell Activation in Patients With Systolic Heart Failure.

Colombo, Paolo C; Castagna, Francesco; Onat, Duygu; Wong, Ka Yuk; Harxhi, Ante; Hayashi, Yacki; Friedman, Richard A; Pinsino, Alberto; Ladanyi, Annamaria; Mebazaa, Alexander; Jelic, Sanja; Arrigo, Mattia; Lejemtel, Thierry H; Papapanou, Panos; Sabbah, Hani N; Schmidt, Ann Marie; Yuzefpolskaya, Melana; Demmer, Ryan T.

J Card Fail ; 30(4): 580-591, 2024 Apr.

Article in English | MEDLINE | ID: mdl-37625581

5.

Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression.

Schlegel, Martin; Sharma, Monika; Brown, Emily J; Newman, Alexandra A C; Cyr, Yannick; Afonso, Milessa Silva; Corr, Emma M; Koelwyn, Graeme J; van Solingen, Coen; Guzman, Jonathan; Farhat, Rubab; Nikain, Cyrus A; Shanley, Lianne C; Peled, Daniel; Schmidt, Ann Marie; Fisher, Edward A; Moore, Kathryn J.

Circ Res ; 129(5): 530-546, 2021 08 20.

Article in English | MEDLINE | ID: mdl-34289717

6.

The receptor for advanced glycation end products and its ligands' expression in OVE26 diabetic sciatic nerve during the development of length-dependent neuropathy.

Zglejc-Waszak, Kamila; Schmidt, Ann Marie; Juranek, Judyta K.

Neuropathology ; 43(1): 84-94, 2023 Feb.

Article in English | MEDLINE | ID: mdl-35915909

7.

Leukocyte Heterogeneity in Adipose Tissue, Including in Obesity.

Weinstock, Ada; Moura Silva, Hernandez; Moore, Kathryn J; Schmidt, Ann Marie; Fisher, Edward A.

Circ Res ; 126(11): 1590-1612, 2020 05 22.

Article in English | MEDLINE | ID: mdl-32437300

8.

An Eclectic Cast of Cellular Actors Orchestrates Innate Immune Responses in the Mechanisms Driving Obesity and Metabolic Perturbation.

Arivazhagan, Lakshmi; Ruiz, Henry H; Wilson, Robin A; Manigrasso, Michaele B; Gugger, Paul F; Fisher, Edward A; Moore, Kathryn J; Ramasamy, Ravichandran; Schmidt, Ann Marie.

Circ Res ; 126(11): 1565-1589, 2020 05 22.

Article in English | MEDLINE | ID: mdl-32437306

9.

Journey to a Receptor for Advanced Glycation End Products Connection in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: With Stops Along the Way in the Lung, Heart, Blood Vessels, and Adipose Tissue.

Roy, Divya; Ramasamy, Ravichandran; Schmidt, Ann Marie.

Arterioscler Thromb Vasc Biol ; 41(2): 614-627, 2021 02.

Article in English | MEDLINE | ID: mdl-33327744

10.

MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging.

Afonso, Milessa Silva; Verma, Narendra; van Solingen, Coen; Cyr, Yannick; Sharma, Monika; Perie, Luce; Corr, Emma M; Schlegel, Martin; Shanley, Lianne C; Peled, Daniel; Yoo, Jenny Y; Schmidt, Ann Marie; Mueller, Elisabetta; Moore, Kathryn J.

Arterioscler Thromb Vasc Biol ; 41(4): 1360-1373, 2021 04.

Article in English | MEDLINE | ID: mdl-33657886

11.

The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications.

Ramasamy, Ravichandran; Shekhtman, Alexander; Schmidt, Ann Marie.

Int J Mol Sci ; 23(9)2022 Apr 21.

Article in English | MEDLINE | ID: mdl-35562970

12.

AgeR deletion decreases soluble fms-like tyrosine kinase 1 production and improves post-ischemic angiogenesis in uremic mice.

Dupont, Vincent; Al-Rifai, Rida; Poitevin, Gael; Ortillon, Jeremy; Jayyosi, Laura; Terryn, Christine; Francois, Caroline; Rieu, Philippe; Fritz, Günter; Boulagnon-Rombi, Camile; Fichel, Caroline; Schmidt, Ann Marie; Tournois, Claire; Nguyen, Philippe; Touré, Fatouma.

Angiogenesis ; 24(1): 47-55, 2021 02.

Article in English | MEDLINE | ID: mdl-32989644

13.

Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1^G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner.

MacLean, Michael; Juranek, Judyta; Cuddapah, Swetha; López-Díez, Raquel; Ruiz, Henry H; Hu, Jiyuan; Frye, Laura; Li, Huilin; Gugger, Paul F; Schmidt, Ann Marie.

J Neuroinflammation ; 18(1): 139, 2021 Jun 15.

Article in English | MEDLINE | ID: mdl-34130712

14.

AGE/RAGE/DIAPH1 axis is associated with immunometabolic markers and risk of insulin resistance in subcutaneous but not omental adipose tissue in human obesity.

Ruiz, Henry H; Nguyen, Anh; Wang, Chan; He, Linchen; Li, Huilin; Hallowell, Peter; McNamara, Coleen; Schmidt, Ann Marie.

Int J Obes (Lond) ; 45(9): 2083-2094, 2021 09.

Article in English | MEDLINE | ID: mdl-34103691

15.

S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus.

Kawakami, Ryo; Katsuki, Shunsuke; Travers, Richard; Romero, Dayanna Carolina; Becker-Greene, Dakota; Passos, Livia Silva Araujo; Higashi, Hideyuki; Blaser, Mark C; Sukhova, Galina K; Buttigieg, Josef; Kopriva, David; Schmidt, Ann Marie; Anderson, Daniel G; Singh, Sasha A; Cardoso, Luis; Weinbaum, Sheldon; Libby, Peter; Aikawa, Masanori; Croce, Kevin; Aikawa, Elena.

Arterioscler Thromb Vasc Biol ; 40(8): 1838-1853, 2020 08.

Article in English | MEDLINE | ID: mdl-32460581

16.

Diabetes and Cardiovascular Complications: The Epidemics Continue.

López-Díez, Raquel; Egaña-Gorroño, Lander; Senatus, Laura; Shekhtman, Alexander; Ramasamy, Ravichandran; Schmidt, Ann Marie.

Curr Cardiol Rep ; 23(7): 74, 2021 06 03.

Article in English | MEDLINE | ID: mdl-34081211

17.

Multiomics of World Trade Center Particulate Matter-induced Persistent Airway Hyperreactivity. Role of Receptor for Advanced Glycation End Products.

Haider, Syed H; Veerappan, Arul; Crowley, George; Caraher, Erin J; Ostrofsky, Dean; Mikhail, Mena; Lam, Rachel; Wang, Yuyan; Sunseri, Maria; Kwon, Sophia; Prezant, David J; Liu, Mengling; Schmidt, Ann Marie; Nolan, Anna.

Am J Respir Cell Mol Biol ; 63(2): 219-233, 2020 08.

Article in English | MEDLINE | ID: mdl-32315541

18.

Diabetes Mellitus and Cardiovascular Disease.

Schmidt, Ann Marie.

Arterioscler Thromb Vasc Biol ; 39(4): 558-568, 2019 04.

Article in English | MEDLINE | ID: mdl-30786741

19.

Recipients of the 2024 Early Career Investigator Awards.

Schmidt, Ann Marie.

Arterioscler Thromb Vasc Biol ; 44(5): 1001, 2024 May.

Article in English | MEDLINE | ID: mdl-38299359

20.

RAGE Mediates Cholesterol Efflux Impairment in Macrophages Caused by Human Advanced Glycated Albumin.

Machado-Lima, Adriana; López-Díez, Raquel; Iborra, Rodrigo Tallada; Pinto, Raphael de Souza; Daffu, Gurdip; Shen, Xiaoping; Nakandakare, Edna Regina; Machado, Ubiratan Fabres; Corrêa-Giannella, Maria Lucia Cardillo; Schmidt, Ann Marie; Passarelli, Marisa.

Int J Mol Sci ; 21(19)2020 Oct 01.

Article in English | MEDLINE | ID: mdl-33019603

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The IRG1-itaconate axis protects from cholesterol-induced inflammation and atherosclerosis.

Obesity research: Moving from bench to bedside to population.

Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity.

Experimentally Induced Peripheral Venous Congestion Exacerbates Inflammation, Oxidative Stress, and Neurohormonal and Endothelial Cell Activation in Patients With Systolic Heart Failure.

Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression.

The receptor for advanced glycation end products and its ligands' expression in OVE26 diabetic sciatic nerve during the development of length-dependent neuropathy.

Leukocyte Heterogeneity in Adipose Tissue, Including in Obesity.

An Eclectic Cast of Cellular Actors Orchestrates Innate Immune Responses in the Mechanisms Driving Obesity and Metabolic Perturbation.

Journey to a Receptor for Advanced Glycation End Products Connection in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: With Stops Along the Way in the Lung, Heart, Blood Vessels, and Adipose Tissue.

MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging.

The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications.

AgeR deletion decreases soluble fms-like tyrosine kinase 1 production and improves post-ischemic angiogenesis in uremic mice.

Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1^G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner.

AGE/RAGE/DIAPH1 axis is associated with immunometabolic markers and risk of insulin resistance in subcutaneous but not omental adipose tissue in human obesity.

S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus.

Diabetes and Cardiovascular Complications: The Epidemics Continue.

Multiomics of World Trade Center Particulate Matter-induced Persistent Airway Hyperreactivity. Role of Receptor for Advanced Glycation End Products.

Diabetes Mellitus and Cardiovascular Disease.

Recipients of the 2024 Early Career Investigator Awards.

RAGE Mediates Cholesterol Efflux Impairment in Macrophages Caused by Human Advanced Glycated Albumin.